Search results for "early stage"

showing 10 items of 11 documents

Self-Reported Long-Term Autonomic Function After Laparoscopic Total Mesometrial Resection for Early-Stage Cervical Cancer: A Multicentric Study.

2017

ObjectivesThis multicentric retrospective study investigates the early and long-term self-reported urinary, bowel, and sexual dysfunctions in early-stage cervical cancer patients who submitted to laparoscopic total mesometrial resection (L-TMMR), total laparoscopic radical hysterectomy, vaginal-assisted laparoscopic radical hysterectomy, and laparoscopic-assisted radical vaginal hysterectomy.MethodsCervical cancer patients, FIGO (International Federation of Gynecology and Obstetrics) stage IA2–IB1/IIA1 who submitted to nerve-sparing radical hysterectomy were recruited. Pelvic functions were assessed within 30 days (early outcome) and 12 months after surgery (long-term outcome).ResultsTwo hu…

Adultmedicine.medical_specialtyStress incontinenceConstipationSexual Dysfunctionmedia_common.quotation_subjectUrinary systemPhysiologicalUrinationUterine Cervical NeoplasmsAutonomic Nervous SystemHysterectomyUrination03 medical and health sciencesYoung Adult0302 clinical medicinemedicineHumansMesenteryRadical Hysterectomymedia_commonAgedNeoplasm StagingRetrospective StudiesCervical cancerAdult; Aged; Autonomic Nervous System; Female; Humans; Hysterectomy; Intestinal Diseases; Laparoscopy; Mesentery; Middle Aged; Neoplasm Staging; Retrospective Studies; Self Report; Sexual Dysfunction Physiological; Urination; Uterine Cervical Neoplasms; Young Adult; Oncology; Obstetrics and Gynecology030219 obstetrics & reproductive medicinebusiness.industryObstetrics and GynecologyRetrospective cohort studyPerioperativeMiddle Agedmedicine.diseaseSurgerycervical cancer total mesomeria resection early stageIntestinal DiseasesSexual Dysfunction PhysiologicalSettore MED/40 - GINECOLOGIA E OSTETRICIAOncology030220 oncology & carcinogenesisFemaleLaparoscopySelf Reportmedicine.symptombusinessInternational journal of gynecological cancer : official journal of the International Gynecological Cancer Society
researchProduct

Prevalence of lymph nodes in the parametrium of radical vaginal trachelectomy (RVT) specimen

2011

Objective: In order to evaluate radicality in fertility preserving surgery in women with early invasive cervical cancer we analyzed the parametrium of specimens of patients treated by radical vaginal trachelectomy for the presence of lymph nodes. We tried to identify morphologic factors associated with the presence of parametrial lymph nodes. Methods: We analyzed surgical specimens of 112 patients who underwent radical trachelectomy between June 2004 and April 2009 at the Department of Gynecologic Oncology at Charité Campus Benjamin Franklin and Campus Mitte. All parametrial tissue was step sectioned and a total of 1878H&E stained histological sections were analyzed. Results: In 8 patients …

Adultmedicine.medical_specialtyUterine Cervical NeoplasmBroad LigamentEarly stage cervical cancerUterine Cervical NeoplasmsHistopathologyRadical vaginal trachelectomyTrachelectomyGynecologic oncologyMetastasisGynecologic Surgical ProceduresGynecologic Surgical ProcedureParametriummedicinePrevalenceHumansCervical cancerbusiness.industryParametrialLymph NodeObstetrics and GynecologyLymphatic Metastasimedicine.diseaseImmunohistochemistrySurgeryEarly stage cervical cancer; Radical vaginal trachelectomy; Parametrial resectionmedicine.anatomical_structureParametrial lymph nodeOncologyLymphatic MetastasisParametrial resectionHistopathologyFemaleLymph NodesLymphbusinessHuman
researchProduct

Beyond sentinel node algorithm. Toward a more tailored surgery for cervical cancer patients

2016

none 12 Nowadays cervical cancer is frequently diagnosed at early stage. For these patients lymph node metastasis (LNM) is considered the most important prognostic factor. During the last decade many efforts have been made to reduce rate of complications associated with lymphadenectomy (LND). A great interest has arisen in sentinel lymph node (SLN) biopsy as a technique able to decrease number of LND performed and, at the same time, to assess lymph nodal status. High diagnostic performances have been reached thanks to SLN surgical algorithm. However, despite the efforts, about 25% of these patients undergo at least unilateral LND to meet NCCN recommendations. Data of women with Internationa…

Cervical cancer; early stage; lymphadenectomy; sentinel lymph node; Oncology; Radiology Nuclear Medicine and Imaging; Cancer ResearchCancer Researchmedicine.medical_treatmentUterine Cervical NeoplasmsCervical cancer; early stage; lymphadenectomy; sentinel lymph node0302 clinical medicinesentinel lymph nodeNuclear Medicine and ImagingMedicineStage (cooking)Original ResearchCervical cancer030219 obstetrics & reproductive medicinemedicine.diagnostic_testSentinel nodeMiddle Agedearly stagePrognosisOncology030220 oncology & carcinogenesisLymphatic MetastasisFemaleRadiologyAlgorithmAlgorithmsAdultmedicine.medical_specialtySentinel lymph nodeUnnecessary ProceduresHysterectomy03 medical and health sciencesBiopsyHumansRadiology Nuclear Medicine and imagingRadical HysterectomyAgedNeoplasm StagingRetrospective StudiesHysterectomybusiness.industrySentinel Lymph Node BiopsyClinical Cancer Researchmedicine.diseaseSurgerySettore MED/40 - GINECOLOGIA E OSTETRICIAlymphadenectomyCervical cancerLymph Node ExcisionLymphadenectomyNeoplasm Gradingbusiness
researchProduct

Attending an activity center: positive experiences of a group of home-dwelling persons with early-stage dementia

2014

Ulrika Söderhamn,1 Live Aasgaard,2 Bjørg Landmark2,3 1Centre for Caring Research Southern Norway, Faculty of Health and Sport Sciences, University of Agder, Grimstad, 2Institute of Research and Development for Nursing and Care Services, Municipality of Drammen, 3Faculty of Health, Buskerud and Vestfold University College, Drammen, Norway Background: In Norway, there is a focus on home-dwelling people with dementia receiving the opportunity to participate in organized meaningful activities. The aim of this study was to elucidate the experiences of home-dwelling persons with early-stage dementia who attend an activity center and participate in adapted phy…

MaleGerontologymedicine.medical_specialtycontent analysisAlternative medicinePsychological interventionHome dwellingactivity centermedicineHumansInterpersonal RelationsExerciseAgedOriginal ResearchAged 80 and overphysical and social activitiesNorwaybusiness.industryVDP::Medical disciplines: 700::Clinical medical disciplines: 750::Geriatrics: 778General MedicineMiddle AgedEarly stage dementiaSocial ParticipationPeer reviewPatient SatisfactionClinical Interventions in AgingDementiaFemaleIndependent LivingexperiencesGeriatrics and Gerontologybusinessqualitative researchQualitative researchClinical Interventions in Aging
researchProduct

Neoadjuvant chemotherapy for stage IIIA-N2 non-small cell lung cancer

2005

Neoadjuvant chemotherapy in potentially resectable stage IIIA-N2 non-small cell lung cancer (NSCLC) has become standard of treatment in the last years. Two randomised pioneer phase III trials conducted with second generation platinum combinations had demonstrated an advantage in survival of induction chemotherapy followed by surgery versus surgery alone. Subsequently, a wide number of phase II studies with third generation platinum-based doublets or triplets have increased the evidence of the activity as well as the good tolerability of this approach. Nowadays, the main topics of ongoing clinical research are to assess the role of induction chemotherapy in early stage disease, and the role …

Oncologystage IIIA-N2medicine.medical_specialtyLung NeoplasmsPaclitaxelmedicine.medical_treatmentDocetaxelNSCLCDeoxycytidinemolecular markers analysisCarcinoma Non-Small-Cell LungInternal medicineAntineoplastic Combined Chemotherapy ProtocolsHumansMedicineStage (cooking)Lung cancerNeoplasm StagingCisplatinChemotherapybusiness.industryInduction chemotherapyHematologymedicine.diseaseearly stageGemcitabineRadiation therapyneoadjuvant radiotherapyOncologyTolerabilityDocetaxelChemotherapy AdjuvantRadiotherapy AdjuvantTaxoidsCisplatinbusinessmedicine.drugneoadjuvant chemotherapy
researchProduct

Curative therapies for hepatocellular carcinoma: an update and perspectives.

2015

Curative treatments, including liver transplantation, surgical resection and percutaneous treatments, are the recommended therapies in BCLC-0 (Barcelona Clinic of Liver Cancer) or BCLC-A hepatocellular carcinoma (HCC). This review provides an overview of some issues of clinical importance concerning curative treatments in HCC.

RFASurgical resectionAblation TechniquesPathologymedicine.medical_specialtyPercutaneousCarcinoma HepatocellularAblative therapymedicine.medical_treatmentLiver transplantationResection03 medical and health sciences0302 clinical medicinemedicineHepatectomyHumansPharmacology (medical)resectionHCCAblative therapy; early stage; HCC; liver transplant; PEI; resection; RFA; Ablation Techniques; Carcinoma Hepatocellular; Hepatectomy; Humans; Liver Neoplasms; Liver Transplantation; Oncology; Pharmacology (medical)business.industryCarcinomaLiver NeoplasmsHepatocellularearly stagemedicine.diseasedigestive system diseasesPEISurgeryLiver Transplantationliver transplantOncology030220 oncology & carcinogenesisHepatocellular carcinoma030211 gastroenterology & hepatologyLiver cancerbusinessExpert review of anticancer therapy
researchProduct

Robotic versus laparoscopic radical hysterectomy in early cervical cancer: A case matched control study

2018

Abstract Background This study aims at evaluating the feasibility, surgical outcome and oncological results observed after robotic radical hysterectomy (RH) compared to laparoscopy for patients with early stage cervical cancer (ECC) patients. Methods Between January 2010 and October 2016, 210 patients underwent RH for treatment of ECC: 70 underwent robotic approach (Cases), and 140 underwent laparoscopic approach (Controls). Results There was no statistically significant difference between the two approaches with regard to clinical patient characteristics and in terms of extent of RH and rate of pelvic and aortic lymphadenectomy. Operative time was significantly longer in the robotic versus…

Uterine Cervical NeoplasmTime Factorsmedicine.medical_treatmentEarly stage cervical cancerUterine Cervical Neoplasms0302 clinical medicinePostoperative ComplicationsRetrospective StudieLaparotomy80 and overMedicineEarly Detection of CancerEarly stage cervical cancer; Laparoscopy; Robotic surgery; Adult; Aged; Aged 80 and over; Female; Humans; Hysterectomy; Incidence; Italy; Laparoscopy; Middle Aged; Postoperative Complications; Retrospective Studies; Robotics; Survival Rate; Time Factors; Uterine Cervical Neoplasms; Young Adult; Early Detection of Cancer; Neoplasm Staging; Surgery; OncologyAged 80 and over030219 obstetrics & reproductive medicineIncidenceGeneral MedicineRoboticsMiddle AgedSurvival RateOncologyItaly030220 oncology & carcinogenesisFemaleHumanAdultmedicine.medical_specialtyTime FactorHysterectomy03 medical and health sciencesYoung AdultHumansRobotic surgeryRadical surgeryRadical HysterectomySurvival rateRetrospective StudiesAgedNeoplasm StagingHysterectomybusiness.industryRobotic surgeryPerioperativeSurgeryRoboticSettore MED/40 - GINECOLOGIA E OSTETRICIASurgeryLymphadenectomyLaparoscopyPostoperative Complicationbusiness
researchProduct

An empirical evaluation of business model canvas in software startups : a team perspective

2019

Business model canvas is a commonly used tool among software startups. The tool aims to help companies develop business models and new strategies. Even though the model has been widely adapted among software startups a lack of scientific research regarding the topic can be found. This thesis evaluates how the business model canvas should be further devel- oped when it comes to early stage software startups. This is done with a team perspective. First, an understanding of software startups is created. Secondly, based on the literature the Team Component is presented including the con- structs of resources, networks, self-organization and way of working. After this, the scope is widened to bu…

business model canvasearly stage software startupsoftware developmentlean manufacturinglean-ajattelustartup companiesohjelmistokehitysteamsstartup-yrityksettiimit
researchProduct

Global and local stressors on community succession in the Mediterranean intertidal zone

late stages of intertidal successionSettore BIO/07 - EcologiaDiffusion Boundary Layerocean acidificationglobal warmingstorm waves.Early stages of intertidal successionchemical composition of recruiting surfacelocal disturbanceMediterranean Seaglobal stressorD. cristatumrecovery dynamicgrazingpatches dynamicvermetid reef
researchProduct

Volunteering in dementia care – a Norwegian phenomenological study

2012

Ulrika Söderhamn1, Bjørg Landmark2,3, Live Aasgaard2, Hilde Eide3, Olle Söderhamn11Center for Caring Research – Southern Norway, Faculty of Health and Sport Sciences, University of Agder, Grimstad, Norway; 2Institute of Research and Development for Nursing and Care Services, Municipality of Drammen, Drammen, Norway; 3Faculty of Health Sciences, Buskerud University College, Drammen, NorwayIntroduction: The number of people suffering from dementia will increase dramatically in the future, and this will be a great challenge and concern for health care services. It is assumed that volunteers will strengthen community health care services more in the future…

medicine.medical_specialtyAlternative medicineNorwegianBioinformaticsPhenomenology (philosophy)early stage dementiaNursingCommunity health careHealth careMedicineDementiaGeneral NursingOriginal Researchactivity early stage dementia phenomenology voluntary workbusiness.industryactivityJournal of Multidisciplinary Healthcarevoluntary workGeneral MedicineEarly stage dementiamedicine.diseaselanguage.human_languagePeer reviewlanguagephenomenologyVDP::Medical disciplines: 700::Health sciences: 800::Community medicine Social medicine: 801businessJournal of Multidisciplinary Healthcare
researchProduct